Recent News

The Impact of Inflammation on Cellular Aging

Research Background Our laboratory aims to investigate the intersection of psychological stress, nutrition, and physical activity to understand how stress gets “under your skin” and contributes to disease, including cardiovascular disease and various types of cancer. To address these questions, we are conducting a number of research projects focused on telomere length, which are a […]

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New KHS Research: The Dangers of Sitting

KHS instructor and exercise physiologist Matthew Scott publishes new research on how prolonged sedentary behavior can negatively impact our health. Get more information from VCU News: http://www.news.vcu.edu/article/VCU_instructor_and_exercise_physiologist_Binge_sitting_is_bad  

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Undergraduates in the Lab

Virginia Commonwealth University is committed to bringing the resources of a research institution to bear on student learning opportunities. A key component of this commitment is engaging our undergraduate students in research activities with an outstanding faculty. To assist in this endeavor, the Department of Kinesiology and Health Sciences is committed to enhancing VCU’s intellectual climate and […]

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Exercise-induced lactate and immune cell function

Primary Investigator: Dr. Lee Franco Other Investigators: Anson Blanks Cardiovascular disease may be characterized by a skewing of macrophage polarization from the anti-inflammatory M2 phenotype towards the pro-inflammatory M1 phenotype. Lactate, a by-product of cell metabolism which is increased in circulation during intense exercise, has been shown to skew the monocyte to macrophage transition towards […]

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VCU-ART3

Primary Investigator: Dr. Lee Franco Other Investigators: Anson Blanks Chronic heart failure (CHF) is often a result of myocardial damage following ST-segment elevation myocardial infarction (STEMI). This damage is due in part to the recruitment of inflammatory monocytes by activation of the CCR2 receptor. Previous studies have suggested that Anakinra, an IL-1β receptor antagonist, may […]

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LPS-Induced iNOS mRNA and Pro-Apoptotic Signaling

Primary Investigator: Dr. Ed Acevedo Other Investigators: Aaron Slusher, Tiffany Zuniga This study seeks to understand the potential role of iNOS in the maintenance of cellular homeostasis and to investigate how the effect of aerobic exercise training may alter iNOS mRNA expression in leukocytes, thereby influencing the pro-apoptotic pathway to sustain cellular regulation.

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PTSD, Vascular Function, and Exercise Tolerance Study

Primary Investigator: Dr. Ryan Garten This study aims to identify the impact of post-traumatic stress disorder (PTSD) on peripheral vascular function, oxidative stress/inflammation, and exercise tolerance in young individuals.

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Reductive Stress Study

Primary Investigator: Dr. Ryan Garten This study examines the impact of 28 days of antioxidant supplementation on vascular function and exercise tolerance in young, healthy individuals.

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Contact the Lab

The Exercise Physiology Research Lab is located at the 500 Academic Center building on VCU’s Monroe Park Campus. Our address is 1020 West Grace Street, Richmond, Virginia 23223 Questions? Email one of our lab’s co-directors: Dr. Lee Franco (francorl@vcu.edu) Dr. Ryan Garten (rsgarten@vcu.edu)

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