Paula Rodriguez Miguelez

Paula Rodriguez-Miguelez, Ph.D.

Assistant Professor
prodriguezmig@vcu.edu
(804) 828-1948
500 Academic Centre, Room 111

Education

2018 - Postdoctoral Fellowship, Clinical Vascular Physiology, Augusta University, GA.

2014 - Ph.D. in Biomedical Science with International Mention, University of Leon, Spain.
            (International mention completed at Karolinska Institute, Sweden).

2011 - M.Sc. in Innovation in Biomedical Science, University of Leon, Spain.

2011 - Post Bachelor thesis in Biomedical Science, University of Leon, Spain.

2010 - B.Sc. in Applied Biomedical Science, Nottingham Trent University, United Kingdom.

2009 - B.SC. in Biotechnology, University of Leon, Spain.

Teaching Assignments

HPEX 353 - Disease Trends, Prevention and Control

Research Interests

Dr. Rodriguez’s research interests are focused on understanding the physiological and molecular mechanisms that contribute to the development of vascular dysfunction and exercise intolerance in different populations.

Select Publications

Rodriguez-Miguelez P, Ishii H, Seigler N, Crandall R, Thomas J, Forseen C, McKie K, Harris RA. Sildenafil Improves Exercise Capacity in Patients with Cystic Fibrosis: A Proof of Concept Clinical Trial. Ther Adv Chronic Disease. In Press.

Rodriguez-Miguelez P, Seigler N, Tucker Ma, Csanyi G, McKie KT, Forseen C, Harris RA. Sildenafil Improves Vascular Endothelial Function in Patients with Cystic Fibrosis. Am J Physiol Heart Circ Physiology. 2018 Aug 31. 

Rodriguez-Miguelez P, Gregg J, Seigler N, Bass L, Thomas J, Pollock J, Sullivan J, Dillard T, Harris RA. Acute Tetrahydropterin Restores Endothelial Function in Patients with COPD. Chest.  2018 Sep; 154(3): 597-606. 

Rodriguez-Miguelez P, Erickson M, McCully K, Harris RA. Skeletal Muscle Oxidative Capacity Is Altered in Patients with Cystic Fibrosis. J Physiol. 2017 Mar 1;595(5):1423-1425. 

Irimia JM, Guerrero M, Rodriguez-Miguelez P, Cadefau J, Tesch PA, Cusso R, Fernandez-Gonzalo R. Journal of Applied Physiology. Metabolic Adaptations in Skeletal Muscle after 84 days Bed Rest With and Without Concurrent Flywheel Resistance Exercise. J Appl Physiol. 2017 Jan 1;122(1):96-103.

Rodriguez-Miguelez P, Thomas J, Seigler N, Crandall R, McKie KT, Forseen C, Harris RA. Evidences of Microvascular Dysfunction in Patients with Cystic Fibrosis. American Journal of Physiology; Heart and Circulatory Physiology. 2016 April 15.

Rodriguez-Miguelez P, Fernandez-Gonzalo R, Collado PS, Almar M, Martinez-Florez S, Paz JA, Gonzalez-Gallego J, Cuevas M. Whole-body vibration improves the anti-inflammatory status in elderly subjects through toll-like receptor 2 and 4 signaling pathways. Mechanism of Ageing and Development, 2015 Sep;150:12-9.

Rodriguez-Miguelez P, Lima E, Almar M, Cuevas MJ, Gonzalez-Gallego J. Hypoxia-inducible factor-1 modulates the expression of vascular endothelial growth factor and endothelial nitric oxide synthase induced by eccentric exercise. J App Physi, 2015 April 15;118 (8):1075-83

Rodriguez-Miguelez P, Fernandez-Gonzalo R, Collado PS, Almar M, Martinez-Florez S, Paz JA, Gonzalez-Gallego J, Cuevas M. Whole-body vibration improves the anti-inflammatory status in elderly subjects through toll-like receptor 2 and 4 signaling pathways. Mechanism of Ageing and Development, 2015 Sep;150:12-9.

Rodriguez-Miguelez P, Fernandez-Gonzalo R, Almar M, Mejias Y, Rivas A, De Paz JA, Cuevas MJ, Gonzalez-Gallego J. Role of Toll like receptor 2 and 4 signaling pathways on the inflammatory response to resistance training in elderly subjects. Age, 2014 Dec; 36(6):9734. 

Publications listed on PubMed

Awards

2017 - Dr. Lisa Krivickas Clinician Award, 64th ACSM Annual Meeting (Denver, CO).

2017 - Highlighted Clinical Abstract, 64th ACSM Annual Meeting (Denver, CO).

2016 - Inaugural Jack Wilmore Legacy Award, 63rd ACSM Annual Meeting (Boston, MA).

2015 - Finalist Junior Investigator Best Anstract Clinical Research Award, 29th North American Cystic Fibrosis Conference (Phoenix, AZ).

2015 - Award for Excellence in Research by a Postdoctoral Fellow, Georgia Regents University (Augusta, GA).

Grant Support (active and prior)

Title: Improving Cardiovascular Health in Patients with Chronic Obstructive Pulmonary Disease: A mechanistic Approach (2018-2021).
Agency: American Heart Association, Career Development Award
Role: Principal Investigator.

Title: Mechanism of Vascular Dysfunction in Adults who Experienced Adverse Childhood Events (2016-2018).
Agency: American Heart Association, Postdoctoral Fellowship.
Role: Principal Investigator.