Education

• Ph.D., Molecular Medicine and Metabolism, Sapienza University of Rome, Italy.
• M.S., Molecular and Nutritional Biology, Carlo Bo University of Urbino, Italy.
• B.S., Nutrition and Dietetics, Sapienza University of Rome, Italy.

Research Interests

Dr. Carbone's research investigates the role of different dietary interventions, with a focus on fatty acids, and body composition phenotypes on cardiorespiratory fitness and energy metabolism in patients with obesity and heart failure, with a focus on heart failure with preserved ejection fraction. To complete this project, he has received a Career Development Award from the American Heart Association. He is also investigating the effect of glucose-lowering agents such as sodium-glucose co-transporter-2 inhibitors on cardiorespiratory fitness in patients with type 2 diabetes mellitus and heart failure with reduced ejection fraction, for which he has received a Mentored Clinical & Population Research Award from American Heart Association. Dr. Carbone is also a registered dietitian nutritionist (RDN).

Carbone has published more than 170 articles (as of 8/14/2024), including original articles resulting from preclinical and clinical studies as well as reviews, invited reviews and editorials, in addition to 3 book chapters. He serves as the Associate Editor for the Cardiovascular Section for the Journal Diabetes/Metabolism, Research & Reviews (DRMM) (2023 Impact Factor: 4.6) and is part of the editorial board of JACC: Heart Failure (2023 Impact Factor: 10.3), among others. He also serves as peer-reviewer for >50 Journals. He has been a full member of the VCU Institutional Review Board for 9 years. He is also a fellow of the Heart Failure Society of America (HFSA) and the American Society for Parenteral and Enteral Nutrition (ASPEN). He has served as grant reviewer for the National Institutes of Health for the Nutrition and Metabolism in Health and Disease (NMHD) and the Clinical Integrative Cardiovascular and Hematological Sciences (CCHS) study sections. He also served as grant reviewer for the American Heart Association (AHA) and ASPEN. 

Select Publications

• Carbone S, Canada JM, Buckley LF, Trankle CR, Dixon DL, Buzzetti R, Arena R, Van Tassell BW, Abbate A. Obesity Contributes to Exercise Intolerance in Heart Failure with Preserved Ejection Fraction. J Am Coll Cardiol 2016;68(22):2487-2488.
• Carbone S, Canada JM, Buckley LF, Trankle R, Billingsley H, Dixon DL, Mauro AG, Dessie S, Kadariya D, Mezzaroma E, Buzzetti R, Arena R, Van Tassell BW, Toldo S, Abbate A. Dietary Fat, Sugar Consumption and Cardiorespiratory Fitness in Patients with Heart Failure with preserved Ejection Fraction. JACC Basic Transl Sci 2017;2(5):513-25.
• Carbone S, Canada JM, Billingsley HE, Kadariya D, Dixon DL, Trankle CR, Buckley LF, Markley R, Vo C, Medina De Chazal H, Christopher S, Buzzetti R, Van Tassell BW, Abbate A. Effects of Empagliflozin on Cardiorespiratory Fitness and Significant Interaction of Loop Diuretics. Diabetes Obes Metab 2018;20(8):2014-2018.
• Carbone S, Billingsley HE, Canada JM, Kadariya D, Medina de Chazal H, Rotelli B, Potere N, Paudel B, Markley R, Dixon DL, Trankle CR, Van Tassell BW, Celi FS, Abbate A. Unsaturated Fatty Acids to Improve Cardiorespiratory Fitness in Patients with Obesity and Heart Failure with Preserved Ejection Fraction: Results from the UFA-Preserved Pilot Study. JACC Basic Transl Sci 2019;4(4):563-565.
• Carbone S, Billingsley HE, Canada JM, Bressi E, Rotelli B; Kadariya D, Dixon DL, Markley R, Trankle CR, Cooke R, Rao K, Shah K, Medina de Chazal H, Chiabrando JG, Vecchié A, Dell M, Mihalick V, Bogaev R, Hart L, Van Tassell BW, Arena R, Celi FS, Abbate A. The Effects of Canagliflozin compared to Sitagliptin on Cardiorespiratory Fitness in Type 2 Diabetes Mellitus and Heart Failure with Reduced Ejection Fraction: Results of the CANA-HF Study. Diabetes Metab Res Rev 2020;36(8):e3335.
• Billingsley HE, Del Buono MG, Canada JM, Kim Y, Damonte JI, Trankle CR, Halasz G, Mihalick V, Vecchié A, Markley R, Kadariya D, Bressi E, Medina de Chazal H, Chiabrando JG, Mbualungu J, Turlington J, Arena R, Van Tassell BW, Abbate A, Carbone S. Sarcopenic Obesity is Associated with Reduced Cardiorespiratory Fitness Compared to Non-sarcopenic Obesity in Patients with Heart Failure with Reduced Ejection Fraction. Circ Heart Fail 2022;15(10):e009518
• Carbone S. Intramuscular and Intermuscular Adipose Tissue in Older Adults: Non-Cardiac Body Composition Depots and the Risk for Heart Failure. JACC Heart Failure 2022;10(7):494-497.
• Salmons H, Ahmed SI, Billingsley HE, Markley R, Damonte JI, Del Buono MG, Kirkman DL, Bohmke NJ, Franco RL, Garten R, Makkiya M, Abbate A, Carbone S. Skeletal Muscle Quality, Measured via Phase Angle, and Cardiorespiratory Fitness in Patients with Obesity and Heart Failure with Preserved Ejection Fraction. Nutrition 2023;116:112163.
• Carbone S, Abbate A. Inflammation and Cardiorespiratory Fitness in HFpEF: A Decade of Progress. JACC Heart Failure 2024;12(7):1270-1273.

Courses

• HPEX 345
• HPEX 495
• HEMS 600 
• HEMS 604
• HEMS 797
• REMS 692
• REMS 710
• REMS 798

Awards

• Career Development Award, American Heart Association (2016)
• Mentored Clinical and Population Research Award, American Heart Association (2018)
• Rising Stars in Healthcare ‘Under 40’, OurHealth, Richmond, VA (2018)
• Future Leader, Heart Failure Society of America (2019)
• Highly Cited Author, Mayo Clinic Proceedings (2021)
• Fellow (FHFSA), Heart Failure Society of America (HFSA) (2021)
• Top 2% of Scientist Worldwide within their Field by Stanford University (2022)
• Chair, Energy & Macronutrient Metabolism Research Interest Section, American Society for Nutrition (2022-2023)
• Fellow (FASPEN), American Society for Parenteral and Enteral Nutrition (ASPEN) (2023)
• Jay N Cohn (JNC) New Investigator Award, HFSA Annual Scientific Meeting (2023)